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Category 2 designation means the FDA identified these substances as presenting potential safety concerns and deemed them not currently eligible for routine compounding under Sections 503A or 503B of the Federal Food, Drug, and Cosmetic Act

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For instance, experiments in rats revealed that it promoted myelin formation and reduced Wallerian degeneration responses [41, 42] and were, similar to vitamin B1 and B6, also believed to have a neuroprotective effect [42] (Figure 1)