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30-60 days Signs of Degradation Discard the vial immediately if you notice any of these: Cloudy or hazy appearance (should be crystal clear) Visible particles floating or settled at the bottom Color changes—any discoloration means discard it Clumping or precipitation that doesn't dissolve when gently swirled Important When to Stop Signs of allergic reaction—rash, hives, swelling, difficulty breathing (stop immediately, seek emergency care) Significant gynecomastia development that doesn't respond to estrogen management Blood clot symptoms—sudden leg pain/swelling, chest pain, shortness of breath (stop immediately, seek emergency care) Your fertility or TRT goals have been achieved and your doctor recommends discontinuation Unacceptable side effects that don't improve with dose adjustments Development of hormone-sensitive conditions HCG is a prescription medication and should only be used under medical supervision

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The butterfly rash is distinct from the sores and scaly lesions also caused by lupus