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b12 injection triggers migraine People with low are up to 5x more likely to have migraines.

Role of vitamin B12 in energy metabolism and red blood cell formation

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Anti-inflammatory and Immunomodulatory Effects (IL-1β, IL-6, TNF-α) Inflammation is a natural and necessary part of the healing process, but chronic or excessive inflammation can impede tissue repair and contribute to pain and tissue degradation