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Frontiers | The role of ferroptosis in neurodegenerative diseases

10.1016/j.heliyon.2024.e32003 121 SavijokiK.MyllymäkiH.LuukinenH.PaulamäkiL.Vanha-AhoL

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Despite significant progress on detection of haptenation having been made, the direct link between adduct formation and development of an adverse reaction has not been established for many compounds due to the difficulties to fully profile and quantify those low levels adducts, which may be important in determining the quantitative threshold for hypersensitivity